Rosai-Dorfman disease presenting as a breast mass
Article Sidebar
Main Article Content
Abstract
Rosai-Dorfman disease (RDD) is an idiopathic, benign proliferation of histiocytes that can be present in multiple organs such as lymph node, skin, soft tissue, orbit, central nerve system and bone; however, it rarely occurs in the breast. In general, RDD is a painless, firm and poorly defined lesion, which can radiologically mimic a breast cancer and is therefore an important differential consideration. The diagnosis of breast RDD is challenging, especially on a small biopsy specimen. We report a unique case of breast RDD with a literature review including common presentation, differential diagnosis, and recommended management. A high index of suspicion for this rare entity is essential to render a correct diagnosis, thereby avoiding unnecessary diagnostic tests and treatment.
Article Details
Copyright (c) 2019 Dai D, et al.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Rosai J, Dorfman RF. Sinus histiocytosis with massive lymphadenopathy. A newly recognized benign clinicopathological entity. Arch Pathol. 1969; 87: 63-70. Ref.: https://goo.gl/EmbgZ1
Eisen RN, Buckley PJ, Rosai J. Immunophenotypic characterization of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease). Semin Diagn Pathol. 1990; 7: 74-82. Ref.: https://goo.gl/Ezi5o9
Foucar E, Rosai J, Dorfman R. Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): review of the entity. Semin Diagn Pathol. 1990; 7: 19-73. Ref.: https://goo.gl/MxVVWu
Green I, Dorfman RF, Rosai J. Breast involvement by extranodal Rosai-Dorfman disease: report of seven cases. Am J Surg Pathol. 1997; 21: 664-668. Ref.: https://goo.gl/SvL9rt
Mac-Moune Lai F, Lam WY, Chin CW, Ng WL. Cutaneous Rosai-Dorfman disease presenting as a suspicious breast mass. J Cutan Pathol. 1994; 21: 377-382. Ref.: https://goo.gl/BKZXsx
Perera AS, Keleher AJ, Nath M. Rosai-Dorfman disease presenting as a male breast mass. Am Surg. 2007; 73: 294-295. Ref.: https://goo.gl/3bcRKs
Bansal P, Chakraborti S, Krishnanand G, Bansal R. Rosai-Dorfman disease of the breast in a male: a case report. Acta Cyto. 2010; 54: 3493-3452. Ref.: https://goo.gl/j9W7bu
Pérez-Guillermo M, Sola-Pérez J, Rodríguez-Bermejo M. Malacoplakia and Rosai-Dorfman disease: two entities of histiocytic origin infrequently localized in the female breast--the cytologic aspect in aspirates obtained via fine-needle aspiration cytology. Diagn Cytopathol. 1993; 9: 698-704. Ref.: https://goo.gl/q3Z91J
Ng SB, Tan LH, Tan PH. Rosai-Dorfman disease of the breast: a mimic of breast malignancy. Pathology. 2000; 32: 10-15. Ref.: https://goo.gl/j6RXLP
Baladandapani P1, Hu Y, Kapoor K, Merriam L, Fisher PR. Rosai-Dorfman disease presenting as multiple breast masses in an otherwise asymptomatic male patient. Clin Radiol. 2012; 67: 393-395. Ref.: https://goo.gl/VuqCjE
Cha YJ, Yang WI, Park SH, Koo JS. Rosai-Dorfman Disease in the breast with increased IgG4 expressing plasma cells: a case report. Korean J Pathol. 2012; 46: 489-493. Ref.: https://goo.gl/HCxnoa
Delaney EE, Larkin A, MacMaster S, Sakhdari A, DeBenedectis CM. Rosai-Dorfman disease of the breast mimicking cancer. Pathol Res Pract. 2007; 203: 741-744. Ref.: https://goo.gl/Wqueng
Kuzmiak CM, Koomen M, Lininger R, Pisano E. Rosai-Dorfman disease presenting as a suspicious breast mass. AJR Am J Roentgenol. 2003; 180: 1740-1742. Ref.: https://goo.gl/XCrwZ4
Wu YC, Hsieh TC, Kao CH, Chang HW, Wang CH, et al., A mimic of breast lymphoma: extranodal Rosai-Dorfman disease. Am J Med Sci. 2010; 339: 282-284. Ref.: https://goo.gl/vcAHFa
Fu L, Liu M, Song Z, Xu B, Tian J. 18F-fluoro-deoxyglucose positron emission tomography/computed tomography scan findings in Rosai-Dorfman disease with IgG4positive plasma cell infiltration mimicking breast malignancy: a case report and literature review. J Med Case Rep. 2012; 30: 411. Ref.: https://goo.gl/zxixCc
Morkowski JJ, Nguyen CV, Lin P, Farr M, Abraham SC, et al., Rosai-Dorfman disease confined to the breast. Ann Diagn Pathol. 2010; 14: 81-87. Ref.: https://goo.gl/9ZN1f2
Hammond LA, Keh C, Rowlands DC. Rosai-Dorfman disease in the breast, Histopathology. 1996; 29: 582-584. Ref.: https://goo.gl/cH42MS
Soares FA, Llorach-Velludo MA, Andrade JM. Rosai-Dorfman's disease of the breast. Am J Surg Pathol. 1999; 23: 359-360. Ref.: https://goo.gl/1ApvRj
Hummel P, Waisman J, Chhieng D, Yan Z, Cohen JM, et al. Fine-needle aspiration cytology of RosaiDorfman disease of the breast: A case report. Diagn Cytopathol. 1999; 21: 287-291. Ref.: https://goo.gl/YjYaSf
Foucar E, Rosai J, Dorfman RF, Eyman JM. Immunologic abnormalities and their significance in sinus histiocytosis with massive lymphadenopathy. Am J Clin Pathol. 1984; 82: 515-525. Ref.: https://goo.gl/zcjwRX
Chen TD, Lee LY, Rosai-Dorfman disease presenting in the parotid gland with features of IgG4-related sclerosing disease. Arch Otolaryngol Head Neck Surg. 2011; 137: 705-708. Ref.: https://goo.gl/kgcHfo
Roberts SS, Attanoos RL. IgG4+ Rosai-Dorfman disease of the lung. Histopathology. 2010; 56: 662-664. Ref.: https://goo.gl/GpYz4E
Liu L, Perry AM, Cao W, Smith LM, Hsi ED, et al. Relationship between Rosai-Dorfman disease and IgG4-related disease: study of 32 cases. Am J Clin Pathol. 2013; 140: 395-402. Ref.: https://goo.gl/urEMPC
McClain KL1, Natkunam Y, Swerdlow SH. Atypical cellular disorders. Hematology Am Soc Hematol Educ Program. 2004; 283-296. Ref.: https://goo.gl/DHdPHf
Paulli M1, Rosso R, Kindl S, Boveri E, Marocolo D, et al. Immunophenotypic characterization of the cell infiltrate in five cases of sinus histiocytosis with massive lymphadenopathy (RosaiDorfman disease). Hum Pathol. 1992; 23: 647-654. Ref.: https://goo.gl/6RkqJA
Foucar E, Rosai J, Dorfman RF. Sinus histiocytosis with massive lymphadenopathy. An analysis of 14 deaths occurring in a patient registry. Cancer. 1984; 54: 1834-1840. Ref.: https://goo.gl/t4gm98
Chen J, Tang H, Li B, Xiu Q. Rosai-Dorfman disease of multiple organs, including the epicardium: An unusual case with poor prognosis. Heart Lung. 2011; 40: 168-171. Ref.: https://goo.gl/keLLZ1
Tenny SO, McGinness M, Zhang D, Damjanov I, Fan F. Rosai-Dorfman disease presenting as a breast mass and enlarged axillary lymph node mimicking malignancy: a case report and review of the literature. Breast J. 2011; 17: 516-520. Ref.: https://goo.gl/AWJ2qc
Mantilla JG, Goldberg-Stein S, Wang Y. Extranodal Rosai-Dorfman Disease: Clinicopathologic Series of 10 Patients with Radiologic Correlation and Review of the Literature. Am J Clin Pathol. 2016; 145: 211-221. Ref.: https://goo.gl/wumbRy
Pulsoni A, Anghel G, Falcucci P, Matera R, Pescarmona E, et al., Treatment of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): report of a case and literature review. Am J Hematol. 2002; 69: 67-71. Ref.: https://goo.gl/bM22z6
Gwin K, Cipriani N, Zhang X, Schmidt R, Hyjek E. Bilateral breast involvement by disseminated extranodal Rosai-Dorfman disease. Breast J. 2011; 17: 309-311. Ref.: https://goo.gl/UrRwMN
Parkin CKE, Keevil C, Howe M, Maxwell AJ. Rosai-Dorfman disease of the breast. BJR Case Rep. 2015; 1: 20150010. Ref.: https://goo.gl/rNkXY8
Zhou Q, Ansari U, Keshav N, Davis D, Cundiff M. Extranodal manifestation of Rosai-Dorfman disease in the breast tissue. Radiol Case Rep. 2016; 17: 125-128. https://goo.gl/chou1p
Delaney EE, Larkin A, MacMaster S, Sakhdari A, DeBenedectis CM. Rosai-Dorfman Disease of the Breast. Cureus. 2017; 11: e1153. Ref.: https://goo.gl/SYfPYv
El-Attrache B, Gluck B, Heimann A, Kapenhas E. A rarity in breast pathology: First recurrent male case of Rosai-Dorfman disease. Int J Surg Case Rep. 2018; 52: 137-139. Ref.: https://goo.gl/EWym1x
Garces S, Medeiros LJ, Patel KP, Li S, Pina-Oviedo S, et al., Mutually exclusive recurrent KRAS and MAP2K1 mutations in Rosai-Dorfman disease. Mod Pathol. 2017;30:1367-1377. http://tinyurl.com/yxcysy7w
Matter MS, Bihl M, Juskevicius D, Tzankov A. Is Rosai-Dorfman disease a reactive process? Detection of a MAP2K1 L115V mutation in a case of Rosai-Dorfman disease. Virchows Arch. 2017;471:545-547http://tinyurl.com/yxnjurdy