About Brody School of Medicine at East Carolina University, Greenville, NC 27834,

Brody School of Medicine at East Carolina University, Greenville, NC 27834,

Articles by Brody School of Medicine at East Carolina University, Greenville, NC 27834,

Rosai-Dorfman disease presenting as a breast mass

Published on: 18th March, 2019

OCLC Number/Unique Identifier: 8056347532

Rosai-Dorfman disease (RDD) is an idiopathic, benign proliferation of histiocytes that can be present in multiple organs such as lymph node, skin, soft tissue, orbit, central nerve system and bone; however, it rarely occurs in the breast. In general, RDD is a painless, firm and poorly defined lesion, which can radiologically mimic a breast cancer and is therefore an important differential consideration. The diagnosis of breast RDD is challenging, especially on a small biopsy specimen. We report a unique case of breast RDD with a literature review including common presentation, differential diagnosis, and recommended management. A high index of suspicion for this rare entity is essential to render a correct diagnosis, thereby avoiding unnecessary diagnostic tests and treatment.
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