Review Article

Current status, complications and prospects of fecal microbiota transplantation therapy

Tadashi Ohara*

Published: 15 April, 2021 | Volume 5 - Issue 1 | Pages: 004-009

Currently, the emergence of highly virulent mutants in Europe and the United States has caused refractory recurrent Clostridium difficile infection (RCDI) to be a problem in clinical practice. In 2013, the Netherland group demonstrated breakthrough therapeutic efficacy in fecal microbial transplant (FMT) treatment clinical trials for RCDI, and FMT treatment is rapidly gaining attention. In addition to RCDI, FMT treatment has been attempted in various gastrointestinal diseases such as inflammatory bowel disease, irritable bowel syndrome and chronic constipation, as well as extragastrointestinal diseases. In this review, I would like to describe the current status, complications and prospects of FMT treatment.

Read Full Article HTML DOI: 10.29328/journal.apcr.1001021 Cite this Article Read Full Article PDF


Fecal microbiota transplantation treatment; Ulcerative colitis; Crohn’s disease; Irritable bowel syndrome; Chronic constipation; Intestinal flora; Clostridium difficile infection; Dysbiosis


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